Thymosin Beta-4 (synthetic fragment)
A synthetic analog of Thymosin Beta-4 that promotes systemic healing through actin regulation and angiogenesis.
TB-500 is a synthetic peptide corresponding to the actin-binding domain (amino acids 17–23) of Thymosin Beta-4 (TB4), a naturally occurring 43-amino acid peptide found in virtually all human cells. Thymosin Beta-4 is one of the most abundant intracellular peptides in mammals and is the primary G-actin sequestering peptide in cells. TB-500 retains the full biological activity of TB4 in a smaller, more practical fragment. Unlike BPC-157, which has primarily local healing effects at the injection site, TB-500 provides systemic healing effects throughout the body, making it particularly valuable for widespread injuries, systemic inflammation, or tissues that are difficult to inject directly (such as tendons deep within joints or cardiac tissue). TB-500 has demonstrated remarkable healing effects in animal models of cardiac injury, tendon damage, corneal wounds, and neurological injury. It is commonly combined with BPC-157 for comprehensive tissue repair.
* Benefits based on preclinical/animal research unless otherwise noted.
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