Description

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed at the Institute of Molecular Genetics of the Russian Academy of Sciences as an analog of tuftsin (a natural immunomodulatory tetrapeptide). It has been approved in Russia and Ukraine for the treatment of generalized anxiety disorder and as a nootropic agent. Selank is notable for producing robust anxiolytic effects comparable to benzodiazepines in animal models, but without the sedation, cognitive impairment, tolerance development, or withdrawal syndrome associated with benzodiazepine use. This makes it particularly attractive for long-term anxiety management and cognitive enhancement. It has also demonstrated immunomodulatory properties, increasing the activity of natural killer (NK) cells and T-lymphocytes, and has been studied for antiviral effects.

Key Characteristics

Investigated Benefits

* Benefits based on preclinical/animal research unless otherwise noted.