Description

GHK-Cu (Glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide-copper complex found in human plasma, urine, and saliva. First isolated by Dr. Loren Pickart in 1973, it has since become one of the most extensively studied anti-aging peptides. GHK-Cu plasma levels decline significantly with age — from approximately 200 ng/mL at age 20 to 80 ng/mL at age 60 — and this decline correlates with reduced tissue repair capacity and increased inflammatory gene expression. Microarray analysis has shown that GHK-Cu can modulate the expression of over 4,000 human genes (approximately 31% of the genome), resetting the expression profile of aged fibroblasts toward a younger state. Its applications span wound healing, skin rejuvenation, hair follicle stimulation, anti-inflammatory effects, and potential neuroprotective and anti-cancer properties.

Key Characteristics

Investigated Benefits

* Benefits based on preclinical/animal research unless otherwise noted.